María Santi was born in La Plata, Argentina, where she currently lives and works. She received her degree in Plastic Arts in 1995 from the Faculty of Arts Universidad Nacional de La Plata, in Argentina. In 2015, she became a Specialist in Media and Technologies for Pictorial Production at Universidad Nacional de las Artes, in Buenos Aires, Argentina.

She later continued her education by attending the workshops of Ana Eckell and Tulio de Sagastizábal, as well as taking various seminars at Universidad Torcuato di Tella in Buenos Aires. 
 

She has attended several international residencies, including: National Center for Contemporary Art (St. Petersburg, Russia), Arteles Creative Center (Hämeenkyrö, Finland) and GlogauAir (Berlin, Germany)​.
 

Her work has been part of numerous exhibitions, with notable individual shows such as: “Chromohipnótico” at Praxis Gallery (2018), “The Commonplace Can Be Extraordinary” at Praxis New York, and “The Eternal and the Ephemeral” at Praxis Gallery, Buenos Aires.
 

Additionally, Santi has participated in multiples group exhibitions, including: “Fuerza Natural”, at Fondo Nacional de las Artes, Buenos Aires (2015); “Hot Hause” in Leipzig, Germany, and “Nomadismo y Periferia” at La Paternal Espacio Proyecto (Buenos Aires).
 

Santi has been selected for various awards and recognitions, including: Rafaela National Painting Biennial, Poggi Urban Museum; Summa Madrid, Casa Cuadrada Gallery (Madrid, Spain); National Salon of Visual Arts (Drawing) (2014) and the National Salon of Visual Arts (Painting) (2012), both at Palais de Glace in Buenos Aires.